Once inflammation is reduced the secondary vascular narrowing is improved allowing increasing amounts of red blood cells carrying oxygen to reach the hypoxic areas and SPECT scans will once again "light up" turning from blue to yellow.
Then most parents will state what they are doing, e.g. Because dissolved oxygen is not confined to a hemoglobin molecule, it can go wherever "body water goes" and therefore reach 'deeper tissues' more easily and more consistently than ever before Because no test is able to predict which child may and which child may not respond to extra pressure and/or extra oxygen (in contrast to excessive oxygen), I let nature take its course and prescribe a clinical trial of HBOT for all my children Though I let "nature take its course", I would not consider prescribing or administering HBOT to children with autism unless there was good scientific evidence to support its use.
HBOT may have the potential to activate dysfunctional mitochondria and/or to activate "dormant/idling cells" thereby allowing more "mitochondrial product" to be appreciated by the body.
A recent study documented impaired production and abnormal ratios of porphyrins in children with autism.
At times it may actually be the sudden removal of higher than normal oxygen concentrations that the body has adapted to rather than the higher levels of oxygen itself that may stimulate angioneogenesis There are reports that the new vessel formation in the retinas of premature infants who were on high doses of oxygen was stimulated by the rapid removal of oxygen and not from the oxygen itself.
, not only due to the competing mechanisms of vasodilation and vasoconstriction, but also due to decreasing the inflammation that secondarily constricts blood vessel lumens in a closed spac.
"we're using 1.5, 1.75, or 2.0 atmospheres in a hard chamber with 100% oxygen, or we're using a soft chamber (also referred to as a mild chamber) at 1.3 atmospheres 'with or without a mask' to which 'concentrated oxygen' is be supplied at concentrations varying from 24% to 70%." Conventional wisdom states that unless one receives HBOT in a hard chamber with 100% oxygen at atmospheric pressures greater than 1.5 ATA, little or no benefit will be seen. Fortunately such evidence does exist, the body of which continues to accumulate, and the mechanisms of action by which HBOT may work for children with autism, as described below, may already be outdated by the time you read this.