The plan of the Synagogue reflects the particular form of worship with its central bimah and the ark.The synagogue is important for its association with the history of immigrant refugees from Poland and Germany in the 16th century, who had established themselves in the City of London at Great St Helens (1827-8).
It has an Edwardian Baroque façade featuring a Doric portico and pediment.
Around four centuries of Ottoman domination then followed, up to the beginning of the Greek War of Independence in 1821.
Numerous monuments from the Byzantine Years and the Ottoman Occupation Period have been preserved, such as Byzantine and Post-Byzantine churches and monasteries, Ottoman buildings, charming Byzantine and Frankish castles, various other monuments as well as traditional settlements, quite a few of which retain their Ottoman and partly Byzantine structure.
To either side are two rectangular stone staircase towers with stone domes.
The impressive galleried interior is in an Italianate style with Doric and Corinthian columns, and a vaulted ceiling.